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Cannabidiol rather than Cannabis sativa extracts inhibit cell growth and induce apoptosis in cervical cancer cells

Galaxy Groves

Tags #cancer, #sativa, cervical cancer

Cannabidiol rather than Cannabis sativa extracts inhibit cell growth and induce apoptosis in cervical cancer cells

Cannabidiol rather than Cannabis sativa extracts inhibit cell growth and induce apoptosis in cervical cancer cells Sindiswa T. Lukhele and Lesetja R. Motadi Author information Article notes Copyright and License information Disclaimer This article has been cited by other articles in PMC. Associated Data Data Availability Statement Go to: Abstract Background Cervical cancer remains a global health related issue among females of Sub-Saharan Africa, with over half a million new cases reported each year. Different therapeutic regimens have been suggested in various regions of Africa, however, over a quarter of a million women die of cervical cancer, annually. This makes it the most lethal cancer amongst black women and...


In vitro and in vivo efficacy of non-psychoactive cannabidiol in neuroblastoma

Galaxy Groves

Tags #cannabidiol, #neuroblastoma

In vitro and in vivo efficacy of non-psychoactive cannabidiol in neuroblastoma

Original Article Pediatric Oncology In vitro and in vivo efficacy of non-psychoactive cannabidiol in neuroblastoma T. Fisher, PhD*a, H. Golan, MD*,†a, G. Schiby, MD‡, S. PriChen, PhD§, R. Smoum, PhD‖, I. Moshe, MSc*, N. Peshes-Yaloz, PhD#, A. Castiel, PhD#, D. Waldman, MD*†, R. Gallily, PhD**, R. Mechoulam, PhD‖, A. Toren, MD PhD†,††*Pediatric Hemato-Oncology Research Laboratory, Sheba Cancer Research Center, †Department of Pediatric Hemato-Oncology, The Edmond and Lily Safra Children’s Hospital, ‡Department of Pathology, The Chaim Sheba Medical Center, Tel-Hashomer, Israel;, §Pediatric Stem Cell Research Institute, The Chaim Sheba Medical Center, Tel-Hashomer, Israel;, ‖Institute for Drug Research, Hebrew University of Jerusalem, Jerusalem, Israel;, #Cancer Research Center, The Chaim Sheba...


Purple marijuana explained: What you need to know about anthocyanins

Galaxy Groves

Tags anthocyanin, purple

Purple marijuana explained: What you need to know about anthocyanins

By Jorge Cervantes, The Cannabist staff   Question: What’s the deal with purple nugs? Answer: Purple cannabis foliage is the result of three different factors: genetics, temperature and nutrient levels.   Molecular genetics Unlock the genetic code in cannabis and you will find anthocyanins, about 400 water-soluble pigment molecules that are classified as flavonoids. Although “flavonoid” is not a derivative of the word “flavor,” flavonoids have a taste that is slightly astringent. Anthocyanins are present in all plants. You have seen how they influence the bright changes in plant colors when summer turns to fall. These pigments also act as a sunscreen to...


Cannabidiolic acid, a major cannabinoid in fiber-type cannabis, is an inhibitor of MDA-MB-231 breast cancer cell migration

Galaxy Groves

Tags cancer, cbd, cbda, cell migration, cell viability

Cannabidiolic acid, a major cannabinoid in fiber-type cannabis, is an inhibitor of MDA-MB-231 breast cancer cell migration

Cannabidiolic acid, a major cannabinoid in fiber-type cannabis, is an inhibitor of MDA-MB-231 breast cancer cell migration Shuso Takeda,a Shunsuke Okajima,a Hiroko Miyoshi,a Kazutaka Yoshida,a Yoshiko Okamoto,a Tomoko Okada,b Toshiaki Amamoto,c Kazuhito Watanabe,d Curtis J. Omiecinski,e and Hironori Aramakia,* Author information Copyright and License information Disclaimer The publisher's final edited version of this article is available at Toxicol Lett See other articles in PMC that cite the published article. Go to: Abstract Cannabidiol (CBD), a major non-psychotropic constituent of fiber-type cannabis plant, has been reported to possess diverse biological activities, including anti-proliferative effect on cancer cells. Although CBD is obtained from non-enzymatic decarboxylation of its parent molecule, cannabidiolic acid (CBDA), few studies have investigated whether...


Cannabis, Terpenes and the Entourage Effect

Galaxy Groves

Tags #cannabis, #entourageeffect, #terpenes

Cannabis, Terpenes and the Entourage Effect

10.31.17 Cannabis, Terpenes and the Entourage Effect Any given terpene can be found to exist in an amazing variety of different plants. For instance, ß-Caryophyllene is found in black pepper, cloves, some cannabis sativa strains, rosemary and hops. Cannabinoids were originally believed to only exist in family Cannabaceae, but have since been found in other families of plants such as family Linaceae (Flax), and Asteraceae (Echinaceae and Helichrysum). About a dozen plants containing CBD have been identified. The variety of plants producing the CBG-A needed to produce other cannabinoids is unknown at this point, the search is just starting. Not...

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